Bob Hoskins has announced his retirement from acting, aged 69, after being diagnosed with Parkinson’s disease.

The Oscar-nominated star of The Long Good Friday, Mona Lisa and Who Framed Roger Rabbit said he had enjoyed a “wonderful” career and now wished to spend time with his family.

He was diagnosed last autumn with Parkinson’s disease, an incurable condition which causes tremors and unsteadiness. Fellow sufferers include Muhammad Ali and the actor Michael J Fox.

In a statement, the actor’s agent said: “Bob Hoskins wishes to announce that he will be retiring from acting, following his diagnosis of Parkinson’s disease last autumn.

“He wishes to thank all the great and brilliant people he has worked with over the years, and all of his fans who have supported him during a wonderful career.